Base Pairs to Populations
نویسندگان
چکیده
منابع مشابه
Microhydration of Guanine base pairs.
We report spectroscopy of clusters of guanine base pairs with one and two water molecules. We recorded the vibronic spectra of the mass-selected GG(H2O) and GG(H2O)2 clusters using resonant two photon ionization (R2PI) and we used IR-UV double resonance spectroscopy to obtain ground state IR spectra of these clusters. We found that a single water molecule stabilizes one of two structures we had...
متن کاملFlexibility of short DNA helices with finite-length effect: From base pairs to tens of base pairs.
Flexibility of short DNA helices is important for the biological functions such as nucleosome formation and DNA-protein recognition. Recent experiments suggest that short DNAs of tens of base pairs (bps) may have apparently higher flexibility than those of kilo bps, while there is still the debate on such high flexibility. In the present work, we have studied the flexibility of short DNAs with ...
متن کاملDNA: From rigid base-pairs to semiflexible polymers
The sequence–dependent elasticity of double-helical DNA on a nm length scale can be captured by the rigid base–pair model, whose strains are the relative position and orientation of adjacent base– pairs. Corresponding elastic potentials have been obtained from all–atom MD simulation and from high–resolution structural data. On the scale of a hundred nm, DNA is successfully described by a contin...
متن کاملFrequency and isostericity of RNA base pairs
Most of the hairpin, internal and junction loops that appear single-stranded in standard RNA secondary structures form recurrent 3D motifs, where non-Watson-Crick base pairs play a central role. Non-Watson-Crick base pairs also play crucial roles in tertiary contacts in structured RNA molecules. We previously classified RNA base pairs geometrically so as to group together those base pairs that ...
متن کاملSynthetic receptors for CG base pairs.
Hydrogen-bond-mediated complexation of a CG base pair by a hexylureido phthalimide and a hexylureido isoindolin-1-one was studied by (1)H NMR spectroscopy in an organic solvent. Chemical shift data indicate that both receptors effectively bind the CG base pair from the major groove side.
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2017
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-16-2631